Research Article | Open Access
Volume 2024 - 3 | Article ID 253 | http://dx.doi.org/10.51521/IJMHR.2024.31115
Academic Editor: Wendy Yeo
Hrushikesh Dhande1, Roshan
Bodhe1, Swati Lade1, Jayshree Taksande1,*, Milind
J.
Umekar1
1Department of Pharmaceutics,
Smt. Kishoritai Bhoyar,
College of Pharmacy, New Kamptee,
Nagpur (M.S.), India-441 002.
*Author for Correspondence: Dr. Jayshree Taksande, Department of Pharmaceutics, Smt. Kishoritai Bhoyar College of Pharmacy, New Kamptee, Nagpur (Maharashtra), India-441 002; e-mail: jayabtaksande@gmail.com
Citation: Hrushikesh Dhande, Roshan Bodhe, Swati Lade, Jayshree Taksande, Milind J. Umekar, (2024). An Overview of the Usage of Nanostructured Lipid Carriers in the Treatment of Migraines. Int J Med Healthcare Rep, 3(1);1-10.
Copyright: © 2024, Jayshree
Taksande, et al. This is an open-access article distributed under the terms
of the Creative Commons Attribution 4.0 International License, which permits
unrestricted use, distribution and reproduction in any medium, provided the
original author and source are credited.
Abstract
This Review's objective is
to provide a high-level, concise summary of migraine diagnosis, therapy, and
management. One common neurological condition that has a major impact on
people's lives and healthcare systems is migraine. Low drug solubility,
restricted bioavailability, and systemic administration side effects are common
problems with conventional migraine treatment methods. A novel drug delivery
technology known as nanostructured lipid carriers, or NLCs, has emerged as a
viable way to get around these restrictions.
The present status of research
on the use of NLCs in the treatment of migraines is examined in detail in this thorough
review. The review includes an examination of NLCs' special qualities, their
potential advantages in drug delivery, and how they can be used to enhance the pharmacokinetics and therapeutic results
of migraine treatments. The main points are covered in detail, including
enhanced drug solubility, targeted drug delivery, extended- release kinetics, and decreased side effects.
The review also points out current roadblocks and potential future paths in the creation of NLC-based migraine
therapy formulations. The goal of this
synthesis of the available data is to offer insightful guidance to researchers, physicians, and
pharmaceutical companies looking for novel approaches to improve the
effectiveness of treatments for migraine.
Keywords: Migraine, nanostructured
lipid carriers, Controlled release, Solid
lipid nanoparticles, Nose-to-brain delivery, Application
of NLCs.
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