Research Article | Open Access
Volume 2023 - 1 | Article ID 239 | http://dx.doi.org/10.51521/IJMHR.2022.1104
Academic Editor: John Bose
Dr. Shibil
PK*, Prof Dr. Dilip C & Prof Dr. Mohamed Sajid AM
1Department of Pharmacy Practice, Al-Shifa college of Pharmacy,
Perinthalmanna, Kerala
2Department of Laparoscopic and General Surgery, KIMS Al Shifa Hospital,
Perinthalmanna, Kerala
Correspondence: Dr. Shibil PK, Department of Pharmacy Practice, Al-Shifa college of
Pharmacy, Perinthalmanna, Kerala, Email: shibilpharma@gmail.com
Citation: Shibil PK, Dilip C, Mohamed Sajid AM (2022) Evaluation and Guideline
Preparation of Antimicrobial Prophylaxis in General Surgery Departments of A
Tertiary Care Referral Hospital. Int J Med Healthcare Rep, 1(1); 1-6
Copyright: © 2022, Shibil PK, Dilip C, Mohamed Sajid AM., This is an
open-access article distributed under the terms of the Creative Commons
Attribution 4.0 International License, which permits unrestricted use,
distribution and reproduction in any medium, provided the original author and
source are credited
Abstract
Antibiotic
prophylaxis, a very brief course of antibiotics initiated just before the start
of surgical procedures in clean, clean-contaminated and dirty procedures, is
recommended to reduce postoperative infection. This study aimed to explore the
evaluation of antibiotic usage in surgical prophylaxis to the hospital
antibiotic policy and the incidences of Surgical Site Infection (SSI). Data was
collected such as the timing of antibiotic dose, the antibiotic choice used,
duration and type of surgery, etc. A total 100 patients who underwent elective
surgical procedures fulfilled the criteria to be included in the study. The
maximum percentage of cases (16%) were excision. In majority of the cases
cefazolin (34%) and cefoperazone sulbactum combination (33%) was used as
prophylaxis before surgery. Number of post-operative antibiotic prophylaxis
mean =6.40 ± 4.568 dose. Gram-negative organisms isolated more like E. coli and
Staphylococcus. E. coli are more seen in surgical pus than swab. 24 patients
developed SSI. The duration of antibiotic prophylaxis not followed as per
hospital antibiotic policy about 16%, dosing was about 36% and selection was
37%. Number of post-operative antibiotic prophylaxis consumption by DDD for 100
bed days =0.5908± 0.77228 dose. (Range 0-2.08 dose. Staphylococcus aureus was
the most common pathogen found (29.44%). The rate of compliance with surgical
antibiotic prophylaxis guidelines was still very poor. Building local hospital
guidelines for surgical antibiotic prophylaxis, by adopting national or
international guidelines needs to be done to overcome the problem of
non-compliance to guidelines for antibiotic prophylaxis.
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