Extranodal Primary Adrenal Lymphoma – A Case Report

Research Article | Open Access

Volume 2024 - 1 | Article ID 251 | http://dx.doi.org/10.51521/ JORCR.2024/1/101

Extranodal Primary Adrenal Lymphoma – A Case Report

Academic Editor: Wendy Yeo

Received 2024-02-13
Revised 2024-03-04
Accepted 2024-03-06
Published 2024-03-11

Dr. Ayesha Iqbal Maniyar, Dr. Sagarika Nithyanand, Dr. Ram C Alva, Dr. Kirthi Koushik, Dr. MG Janaki, Dr. Arul Ponni, Dr. Mohan Kumar S, Dr. Lithika Lavanya.

Department of Radiation Oncology, M S Ramaiah Medical College and Hospital, Bangalore,India

Corresponding Author: Ayesha Iqbal Maniyar, Department of Radiation Oncology, M S Ramaiah Medical College and Hospital, Bangalore, India

Citation: Ayesha Iqbal Maniyar, Sagarika Nithyanand, Ram C Alva, Kirthi Koushik, MG Janaki, Arul Ponni, Mohan Kumar S, Lithika Lavanya, (2024). Extranodal Primary Adrenal Lymphoma – A Case Report. J Oncol Res Case Rep. 1(1),1-3

Copyright: © 2024, Dr. Ayesha Iqbal Maniyar. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.

Abstract

Primary adrenal lymphoma (PAL) is a highly invasive and an extremely rare malignant disease, accounting for <1% of non-Hodgkin lymphomas. The overall survival (OS) rate is poor and only a few cases of PAL are reported in medical literature. Due to the rarity of the condition, no standardized treatment is available.

Introduction

Adrenal Lymphomas are of two types – primary and secondary adrenal lymphoma. Secondary adrenal lymphoma accounts for 4-5% of all NHL cases. PAL predominantly occurs in males in their sixth to seventh decade of life and involvement of bilateral adrenal glands (70%) is a common finding. The two most common WHO defined PAL subtypes are diffuse large B cell lymphoma (78%) and peripheral T cell lymphoma (7%).PAL is a histologically confirmed lymphoma involving 1 or 2 adrenal glands, with no prior history of lymphoma and if there is involvement of other tissues or lymph nodes in addition to adrenal glands, adrenal lesions should be significantly dominant.²Patients commonly present with abdominal pain, fever, night sweats and weight loss (B symptoms).