Research Article | Open Access
Volume 2021 - 1 | Article ID 176 | http://dx.doi.org/10.51521/JPEM.2021.1105
Academic Editor: John
Rohit Pal
Department of Pharmaceutical Chemistry, ISF College of
Pharmacy, GhalKalan,
Ferozpur G.T. Road MOGA-142001, Punjab
Corresponding
author: Rohit Pal, Department of
Pharmaceutical Chemistry, ISF College of Pharmacy, GhalKalan, Ferozpur G.T. Road MOGA-142001, Punjab, Email: rohitpal.rp096@gmail.com ph:
09760144370
Citation: Rohit Pal, (2021) In-Vitro Evaluation of Anthelmintic
Activity of Nephrolepis cordifolia Leaves. J Pharm
Exper Med, 1(1); 1-6
Copyright:
© 2021, Rohit Pal. This is an open-access article distributed under the terms of the
Creative Commons Attribution 4.0 International License, which permits
unrestricted use, distribution and reproduction in any medium, provided the
original author and source are credited.
ABSTRACT
Nephrolepis cordifolia, is a fern native to northern Australia and Asia. It has
many common names including fishbone fern, tuberous sword fern, tuber ladder
fern, erect sword fern, narrow sword fern and ladder fern, and herringbone
fern. Nephrolepis cordifolia is
a wood fern that typically grows in woodland areas. Both fertile and sterile
fronds are pinnate, up to 3 feet in length and 3 inches wide. There are many
leaflets, or pinnae, ranging from 40-100 mm (1.5 to 4 inches) on each side of
the rachis. Each pinna is oblong to lanceolate with an auricle that overlaps
rachis. Rhizomes are orange/brown to pale brown with linear scales having hair
like tips. stolonis straw coloured and produce small underground tubers. The
presence of tubers distinguishes sword fern from the native Nephrolepis cordifolia fern.
The aim of the present study was to evaluate the anthelmintic activity of
aqueous extract of leaves of Nephrolepis cordifolia. The time of
paralysis and time of death were studied and the activity was compared with
albendazole as reference standard. The aqueous extract of leaves of Nephrolepis cordifolia
exhibited anthelmintic activity as evidenced by decreased paralyzing time and
death time at the concentration of 10 mg/ml.
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