Research Article | Open Access
Volume 2022 - 3 | Article ID 211 | https://dx.doi.org/10.51521/IJMCCR.2022.3309
Academic Editor: John Bose
DR. ROHIT BANGWAL1*, SHIPRA OMAR2,
DR. PRASHANT MATHUR3
1PharmD, Clinical Pharmacologist, Department of Pharmacy Practice, School of Pharmaceutical Sciences,
Shri Guru Ram Rai University, Shri Mahant Indiresh Hospital Dehradun-248001,
Uttarakhand, India.
2Research Scholar, Department
of Pharmacy Practice, School of Pharmaceutical Sciences, Shri Guru Ram Rai
University, Shri Mahant Indiresh Hospital Dehradun-248001, Uttarakhand, India.
3Prof
& Head, Department of Pharmacy Practice, School of Pharmaceutical Sciences,
Shri Guru Ram Rai University, Shri Mahant Indiresh Hospital Dehradun
Uttarakhand, India-248001.
Corresponding Author: Dr. Rohit Bangwal, Pharm D, Clinical Pharmacologist, Department of Pharmacy Practice, Shri Guru Ram Rai
University, Shri Mahant Indiresh Hospital, Dehradun-248001, Uttarakhand, India,
E-mail: rohitbangwal93@gmail.com
Citation: Dr. Rohit Bangwal, Shipra Omar, Dr. Prashant Mathur, (2022).
Ototoxicity Induced by Anti Tubercular Drugs: A Brief Case Report. Int J Med
Clin Case Rep, 3(3), 1-3.
Copyright: © 2022, Dr. Rohit Bangwal. This is an open-access article
distributed under the terms of the Creative Commons Attribution 4.0
International License, which permits unrestricted use, distribution and
reproduction in any medium, provided the original author and source are
credited.
ABSTRACT
Reversible
and irreversible ototoxicity in the potential adverse effect of aminoglycosides
therapy. Long term used Aminoglycosides they can cause Neuromuscular blockage
and nephrotoxicity. In this case study 40 years old female, weighing 50 kg was
brought to the hospital with chief complains of tinnitus, hearing loss, and
vertigo for past 1 week. She had a known relapsed case of smear positive
pulmonary tuberculosis and was taking regular second line anti-tubercular drugs
therapy (Isoniazid, Rifampicin, Pyrazinamide, Ethambutol, and Streptomycin) from
last 3 month. Pulmonologist had stopped inj. Streptomycin 1gm BD but other IInd
line ATT medication was continued. Although there are many case reports already
done previously, Aminoglycosides (AGs), induced ototoxicity particularly in
tuberculosis patients, we come over the first case of AGs induced ototoxicity
in TB patients. In this case patient condition was resolved only after
discontinuation of streptomycin.
KEYWORDS: Aminoglycosides
(AGs), Streptomycin, Ototoxicity.
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