International Journal of Family Medicine and Public Health

Research Article | Open Access

Volume 2025 - 4 | Article ID 295 | http://dx.doi.org/10.51521/IJFMPH.2025.42.124

The Sociobiome: How Socioeconomic Inequality and Food Deserts Shape the Gut–Brain Axis and Community Health

Academic Editor: John Bose

  • Received 2025-10-09
  • Revised 2025-10-18
  • Accepted 2025-10-24
  • Published 2025-11-06

Anna H. Sandhu¹, Arun Radhakrishnan²*, Bob Harinder Sandhu²*

 

 1Founder, SFG Biome, CA, USA

2Research and Development, Sandhus Products, Inc., Livermore, CA, USA

 

Corresponding Author: Arun Radhakrishnan, Bob Harinder Sandhu, Research and Development, Sandhus Products, Inc., Livermore, CA 94551, USA, Emails: arun@sandhus.com; bob@sandhus.com; anna@sfgbiome.com

 

Citation: Anna H. Sandhu, Arun Radhakrishnan, Bob Harinder Sandhu (2025) The Sociobiome: How Socioeconomic Inequality and Food Deserts Shape the Gut–Brain Axis and Community Health. Int J Fam Med Pub Health, 4(2);1-7.

 

Copyrights: © 2025, Anna Sandhu, et al., This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.

 

Abstract:

 

Population health is profoundly shaped by socioeconomic status, and one of the most persistent drivers of inequality is limited access to nutritious food. This review explores how “food deserts” and food insecurity evolve into public health crises through biological as well as social pathways. The gut microbiome, an intricate ecosystem within the human digestive tract emerges as a key mediator of this process. Diets high in calories but poor in nutrients, often the only option for low-income families, disrupt microbial balance and lead to dysbiosis. We introduce the concept of the “sociobiome,” a term describing how social and economic disadvantage become biologically embedded through alterations in gut microbial ecology. This disrupted microbiome influences diverse health outcomes, including mental health challenges, infectious susceptibility, and chronic conditions such as obesity and infertility. Addressing the sociobiome requires a holistic approach that integrates biological science with social policy. By tackling both the social determinants of health and the biological consequences of inequality, we can begin to chart a pathway toward genuine health equity.

 

Keywords: Socioeconomic Status, Food Deserts, Gut Microbiome, Dysbiosis, Sociobiome, Health Inequality, Public Health.

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