Research Article | Open Access
Volume 2025 - 4 | Article ID 295 | http://dx.doi.org/10.51521/IJFMPH.2025.42.124
Academic Editor: John Bose
Anna
H. Sandhu¹, Arun Radhakrishnan²*, Bob Harinder Sandhu²*
1Founder,
SFG Biome, CA, USA
2Research and
Development, Sandhus Products, Inc., Livermore, CA, USA
Corresponding
Author: Arun Radhakrishnan, Bob Harinder Sandhu, Research
and Development, Sandhus Products, Inc., Livermore, CA 94551, USA, Emails:
arun@sandhus.com; bob@sandhus.com; anna@sfgbiome.com
Citation:
Anna H. Sandhu, Arun Radhakrishnan, Bob Harinder Sandhu (2025) The Sociobiome:
How Socioeconomic Inequality and Food Deserts Shape the Gut–Brain Axis and
Community Health. Int J Fam Med Pub Health, 4(2);1-7.
Copyrights:
© 2025, Anna Sandhu, et al., This is an open-access article distributed under the
terms of the Creative Commons Attribution 4.0 International License, which
permits unrestricted use, distribution and reproduction in any medium, provided
the original author and source are credited.
Abstract:
Population health is profoundly shaped by
socioeconomic status, and one of the most persistent drivers of inequality is
limited access to nutritious food. This review explores how “food deserts” and
food insecurity evolve into public health crises through biological as well as
social pathways. The gut microbiome, an intricate ecosystem within the human
digestive tract emerges as a key mediator of this process. Diets high in
calories but poor in nutrients, often the only option for low-income families,
disrupt microbial balance and lead to dysbiosis. We introduce the concept of
the “sociobiome,” a term describing how social and economic disadvantage become
biologically embedded through alterations in gut microbial ecology. This
disrupted microbiome influences diverse health outcomes, including mental
health challenges, infectious susceptibility, and chronic conditions such as
obesity and infertility. Addressing the sociobiome requires a holistic approach
that integrates biological science with social policy. By tackling both the
social determinants of health and the biological consequences of inequality, we
can begin to chart a pathway toward genuine health equity.
Keywords:
Socioeconomic Status, Food Deserts, Gut Microbiome, Dysbiosis, Sociobiome,
Health Inequality, Public Health.