Dr. Ajit Singh

International Research Journal of Clinical Studies and Pharma Trends



Name:  Dr. Ajit Singh


Journal Role: Associate editor

 

Designation: Ph.D. (cardiology)

 

Co-founder & Chief Executive Officer: CliMed Research Solutions,

 

University: Manipal Academy of Higher Education, Manipal University, India.

 

Country: India


Email: ceo@climed.in; Ajithsingh.mcops@gmail.com


Area of Interest: Clinical Research, Cardiology, Pharmacoeconomics and Epidemiological studies.

 

BIOGRAPHY: He completed his Ph.D in Cardiology from Manipal University and now he is a CEO Of his own company CliMed Research Solutions.

 

Education Qualifications

1. Ph.D.; Department of Cardiology, KMC, MAHE, Manipal; 2019 Passed out.

2. Pharm.D; Manipal College Of Pharmaceutical Sciences (MCOPS), Manipal; 2015 Passed out.

3. B.Pharm; Uttar Pradesh Technical University (UPTU), Lucknow; 2012 Passed out.

4. B.Sc; CCS University, Meerut; 2009 Passed out.

 

Work Experience:

1. CEO; CliMed Research Solutions

2. Guest faculty of Cardiac Pharmacology, Manipal Academy of Higher Education, Manipal University, India. [2016-2019]

3. Principal Investigator of Manipal Heart Failure Registry (MHFR) Study [since 2015]

4. Site Coordinator for phase III clinical trial ‘PARALLAX-HF’ by Novartis Pharma Pvt. Ltd. [2017-2019]

5. Investigator of a global Heart Failure clinical study ‘REPORT-HF’ by Novartis Pharma Pvt. Ltd. [2015-2018]

6. Research Associate at Manipal Center for Clinical Research (MCCR) & Department of Cardiology, KMC, Manipal University. [2015-2019]

 

Memberships:

1. European Society of Cardiology Professional MID: 715803

2. American College of Cardiology MID: 3032286

3. International Society for Pharmacoeconomics and Outcomes Research (ISPOR) MID: 28232.

 

Grants & Awards:

1. “Young Scientist Award 2020” by VD Good Professional Association.  

2. “Young Achievers Award 2019” for research by Institute of Scholars, India

3. Department of Science and Technology (DST)- SERB, International Travel Support to attend “Heart Failure 2019 & World Congress on Acute Heart Failure” from 25th May 2019 to 28th May 2019 at Athens, Greece 

4. European Society of Cardiology, Travel grant to attend “Heart Failure 2019 & World Congress on Acute Heart Failure” from 25th May 2019 to 28th May 2019 at Athens,  Greece

5. Indian Council of Medical Research (ICMR) International Travel Support to attend  “Heart Failure 2018 & World Congress on Acute Heart Failure” from 26th May 2018 to 29th May 2018 at Vienna, Austria 

6. European Society of Cardiology, Travel grant to attend “Heart Failure 2018 & World Congress on Acute Heart Failure” from 26th May 2018 to 29th May 2018 at Vienna, Austria

7. Alexander Von Humboldt Indo-German Research Colloquium, Bangalore. (November 22-24, 2017)- Travel and accommodation reimbursement by AVH Foundation, Germany

8. ACC Middle East Conference 2017, Dubai (October 19-21, 2017); grant for registration and participation

9. TMA Pai scholarship for full time PhD at Manipal Academy of Higher Education (From January 2016 to May 2019)

10. Consolation prize for “Optical Device to Monitor blood Platelets Aggregation” at Manipal University Innovation Award held on October 28, 2017

 

Other Journal Involvements:

 

ASSOCIATE EDITOR:

3 Journals including -Asian Journal of Pharmaceutical Research

REVIEWER:

13 Journals including -

1. BMJ Case Reports

2. Clinical Toxicology (Oxford Journals)

3. Clinical Rheumatology (Springer)

4. ISPOR, Value In Health Regional Issues (VIHRI)

5. OMICS Publishers- Cancer Group

PUBLICATIONS:

Google Scholar

https://scholar.google.com/citations?user=wFAkOe4AAAAJ&hI=en&oi=sra

ORCID

https://orcid.org/0000-0001-5767-6384

Researcher id

https://publons.com/researcher/2510909/ajit-singh/

Scopus id

https://www.scopus.com/authid/detail.uri?authorId=57191972713

 

PUBLICATION WORKS

 

1. Azilsartan causing metabolic encephalopathy. Anujith G. Sekhar1, Ajit Singh, Sheetal Chauhan, Kanav Khera, Tom Devasia. J Appl Pharm Sci, 2020; 10(06):123-125.

2. Financial burden of heart failure in a developing country: cost analysis from Manipal Heart Failure Registry, India. Singh A, Chauhan S, Devasia T, Rao Y, Paramasivam G, Shetty PN, Uppunda D, Kareem H. India. J Public Health (Berl.) 2019. https://doi.org/10.1007/s10389-01901141-w

3. Outcomes of the patients of heart failure with reduced ejection fraction receiving inotropic support in initial 6 hours: Insights from Manipal Heart Failure Registry.  Singh A, Chauhan S, Paramasivam G, Devasia T, Rao Y, Shetty PN, Amin N, Uppunda D, Kareem H. J Appl Pharm Sci, 2019; 9(08):011–017.

4. Insulin resistance and the severity of coronary artery disease based on obesity status in stable-angina patients: A cross-sectional analysis.  Uppunda D, Shetty R, Rao P, Razak A, Singh A, Chauhan S, Vadnagarwala H, Prabhu S, Pai U. J Appl Pharm Sci, 2019; 9(07):091–094.

5. Association of Metabolic Obesity and BMI Status with Severity of Angiographic Coronary Artery Disease in Stable Angina Patients. Uppunda D, Shetty RK, Rao P, Razak A, Ravishanker, Shetty K, Chauhan S, Singh A. Journal of Clinical and Diagnostic Research. 2019 Apr, Vol-13(4): OC04-OC08.

6. Impact of socioeconomic status on adverse cardiac events after coronary angioplasty: a cohort study.  Kareem, H., Shetty, P., Devasia, T., Karkala, Y., Paramasivam, G., Guddattu, V., Singh, A. and Chauhan, S. (2018). Heart Asia, 10(2), p.e010960.

7. Manipal lifestyle modification score to predict major adverse cardiac events in postcoronary angioplasty patients.  Devasia, T., Shetty, P.N., Kareem, H., Karkala, Y.R. and Singh, A., 2018. Indian Heart Journal.

8. Baseline NT-ProBNP Level as a Risk Predictor of Contrast Induced-Acute Kidney Injury in Acute Coronary Syndrome Patients Undergoing Primary Angioplasty.  Agarwal, S., Kareem, H., Devasia, T., Mallu, R.R., Paramasivam, G., Singh, A., Shetty, P.N. and Dhanse, S., 2018. Journal of Clinical & Diagnostic Research, 12(3).

9. Glycosylated Haemoglobin as a Risk Predictor of Coronary Artery Disease in Patients with Stable Angina.  Uppunda, D., Shetty, K., Shetty, P.N., Singh, A., Shetty, R.K., Rao, P. And Razak, A., 2018. Journal of Clinical & Diagnostic Research, 12(9).

10. Breast Cancer and the Heart: Burden on the Chest.  Singh, A., Kareem, H., Devasia, T., Khera, K., Chauhan, S., K, Y. and P, G. (2018). Journal of Cardiovascular Disease Research, 9(1), pp.01-04.

11. Cisplatin-Etoposide Induced Myocardial Infarction in a Patient with Small Cell Carcinoma.  Katta, S., Chauhan, S., Singh, A., Shetty, P.N., Kareem, H. and Devasia, T., 2018. Journal of Applied Pharmaceutical Science Vol, 8(05), pp.139-142.

12. Atorvastatin-Induced Hepatotoxicity, Increased by Clopidogrel Stress on CYP450 Enzyme: Understanding the Mechanism through a Case.  Thotakura, S., Singh, A., Khera, K., Chauhan, S. and Devasia, T., 2018. Journal of Applied Pharmaceutical Science Vol, 8(04), pp.168-170.

13. Diabetes Mellitus and Metformin: Fatal Vitamin B12 Deficiency Associated with Anemia and Sepsis in a Young Adult.  Katroth, A., Narayanam, A., Chauhan, S. and Singh, A., 2018. Journal of Applied Pharmaceutical Science Vol, 8(03), pp.165-167.

14. Craniovertebral junction compression due to posterior c1 arch in morquio syndrome: A diagnostic dilemma.  Khan, B.H., Singh, A., Menon, G. and Devasia, T., 2018. Journal of Clinical and Diagnostic Research, 12(4), pp.OJ01-OJ02.

15. Graded Exercise Therapy and Six Minute Walk Test: The Modern Care of Peripheral Vascular Disease.  Singh, A., Kareem, H., Devasia, T., Shetty, P.N., Chauhan, S. and Rao, Y.K., 2017. Research Journal of Pharmacy and Technology, 10(11), pp.4099-4101.

16. Association between the weight loss and anxiety, depression after percutaneous transluminal coronary angioplasty: a need for pre-discharged counseling.  Shetty, P.N., Devasia, T., Rao, Y., Singh, A. and Karim, H., 2017. Asian Journal of Pharmaceutical and Clinical Research, 10(8), pp.323-326.

17. An infant with congenital rubella syndrome in developing India.  Singh, A., Narula, S., Kareem, H. and Devasia, T. (2017). BMJ Case Reports, pp.bcr2017-221665.

18. Descriptive Analysis of Mortality Predictors in H1n1 Influenza in South Indian Patients.  Singh A, Khera K, Agarwal J, Awasthi S, Francis J, Thunga G et al. Infectious Disorders - Drug Targets. 2017;17(2). (PubMed ID: 28403799)

19. Registry Disease Studies in Cardiology in India: The Need of the Hour.  Karkal YR, Tom D, Singh A, Shetty PN.Journal of Cardiovascular Disease Research, Vol 7, Issue 4, Oct-Dec, 2016. 158-9. 

20. “Multiple drugs causing severe anemia in infective endocarditis”  Singh A, Shetty PN, Singh BM, Devasia T. Cardiovasc Hematol Disord Drug Targets. 2016 May 24. (PubMed ID: 27215287)

21. Fatal prognosis of h1n1 influenza in late trimester of pregnancy: descriptive analysis of four cases.  Singh A, Khera K, Agarwal J, Awasthi S, Francis JM, Thunga G.International Journal of Pharmacy and Pharmaceutical Sciences. Vol 8, Issue 8, 2016 (SCOPUS indexed)

22. Cyclophosphamide-induced fatal cytopenia: a case of paraquat poisoning.  Singh A, Rajesh V, Sekhar S, Shastri BA, Saravu K. Int J Pharm Pharm Sci 2016;8(10):296-297 (SCOPUS indexed)

23. “Seizure relapse based upon withdrawal period of Anti-epileptic drugs in Pediatrics patients”.  Rana R, Das S, Ramesh S, Chidambaramnathan S, Swami A, Singh A. Archives of Pharmacy Practice. (DOI: 10.4103/2045-080X.137544)

24. Job's syndrome in a pediatric patient: Case report and the clinical review.  Singh, A., Khera, K., Karanam, A. and Chauhan, S., 2015. Indian Journal of Paediatric Dermatology, 16(2), p.96. 

25. “Assessment of Adherence & Variation in Color and Shape of Oral Antibiotic Pills”.  Rad LV, Rana R, Reddy S, Masoumi SA, Suresh A, Singh A. Asian Academic Research Journal of Multidisciplinary, vol 1, issue 31; 2015.

26. “Neuro-Ophthalmic Complications In Systemic Lupus Erythematosus: Case Analysis and the Literature Review”  Singh A, Khera K, Karanam A, Chauhan S, Rana R. International Journal of Biomedical Research, vol 6, issue 04; 2015. 

27. Design and Evaluation of Transdermal Patch of Felodipine.  Chauhan, Singh A et al. Indo American Journal of Pharmaceutical Research.2015:5(09). 

28. Herpes simplex keratitis-induced endophthalmitis in a patient with AIDS with disseminated tuberculosis.  Singh, A., Khera, K., Inam, S. and Hande, H. (2014). Case Reports, 2014(feb27 1), pp.bcr2013202804. bstracts in Indexed Journals/PubMed: 

29. Healthcare Expenditure of Patients with Heart Failure in a Developing Country.  Singh A, Devasia T, Kareem H, Karkala YR, Chauhan S, Shetty PN, Rao S, Ganesh P, Uppunda D. European Journal of Heart Failure (2019) 21 (Suppl. S1;pp. 277). [IF: 13.26]

30. Drug utilization patterns and its impact on health resource utilization and outcomes among patients with heart failure at a tertiary care hospital in southern India.  Singh A, Devasia T, Kareem H, Karkala YR, Chauhan S, Shetty PN Ganesh P. European Journal of Heart Failure (2019) 21 (Suppl. S1;pp. 393). [IF: 13.26]

31. Role of emergency medical system and early intervention by specialist cardiologist/heart failure expert in influencing the clinical outcomes in Manipal Heart Failure Registry [MHFR] patients.  Singh A, Devasia T, Kareem H, Karkala YR, Chauhan S, Shetty PN, Rao S, Ganesh P, Uppunda D, Shetty KK. European Journal of Heart Failure 2018 May 1 (Vol. 20, pp. 244). [IF: 10.86]

32. Quality of life and mortality on 1 year follow up in Manipal Heart Failure Registry [MHFR].  Singh A, Devasia T, Kareem H, Karkala YR, Chauhan S, Shetty PN, Rao S. European Journal of Heart Failure 2018 May 1 (Vol. 20, pp. 244). [IF: 10.86]

33. Assessment of statins resistance in the patients underwent percutaneous transluminal coronary angioplasty and its association with major adverse cardiac events.  Chauhan, S., Shetty, P., Devasia, T., Karkala, Y., Kareem, H. and Singh, A. (2018). Indian Heart Journal, 70, pp.S30-S31.

34. Assessment of factors associated with major adverse cardiac events after undergoing percutaneous transluminal coronary angioplasty.  Shetty, P., Devasia, T., Kareem, H., Rao K, Y., A., Singh, A., Uppunda, D. and Guddattu, V. (2018). Indian Heart Journal, 70, p.S72.

35. One year outcomes and drug utilization review in Manipal Heart Failure Registry (MHFR) patients.  Singh, A., Devasia, T., Karkala, Y., Chauhan, S., Kareem, H. and Shetty, P. (2018). Indian Heart Journal, 70, p.S52.

36. Metabolically obese status with normal BMI is associated with the prevalence and severity of angiographic CAD in stable-angina patients.  Uppunda, D., Shetty, R., Rao, P. and Singh, A. (2018). Indian Heart Journal, 70, p.S8.

37. Impact of socio-economic status on adverse cardiac events after undergoing percutaneous transluminal coronary angioplasty: A cohort study.  Shetty, P., Devasia, T., Kareem, H., Ganesh, P., Karkalla, Y., Guddattu, V. and Singh, A. (2017).Indian Heart Journal, 69, p.S68.

38. Body Image and Sexual Problem in Young Breast Cancer Patients in South Indian Population.  Singh A, Rana R. Value in Health. 2015;18(7):A824. (IF: 3.28) (PubMed ID: 26534397)

39. Design And Evaluation of Transdermal Patch of Felodipine.  Singh A, Chauhan S. Value in Health. 2015;18(7):A831. (IF: 3.28) (PubMed ID: 26534437)

40. Analysis of Risk Factors of Death in H1N1 Influenza Patients in a Tertiary Care Hospital.  Singh A, Khera K, Agarwal J et al. Value in Health. 2015; 18(3):A229. (IF: 3.28)

41. Patient's Participation in Improvement of Health Related Outcomes: The Better Care Plan.  Singh A, Khera K, Rana R, Chauhan S. Value in Health. 2014;17(7):A453. (IF: 2.891)

42. “Body image and sexual problems in young breast cancer patients in South Indian Population”. Singh A, Rana R, Kumar SD. J Cancer Sci. Therapy (Special Edition). (DOI: 10.4172/1948-5956.S1.037). (IF: 4.203)

 

PROJECTS:

1. Manipal Heart Failure Registry (MHFR): A Long Term, Prospective and Descriptive Study of Heart Failure in a Tertiary Care Hospital in South India

2. Body Image and Sexual Problems in young women with Breast Cancer

3. Better Care Plan- Participation of Caregivers in treatment decision making

4. Manipal lifestyle modification score- Completed

5. Impact of socioeconomic status on adverse cardiac events after coronary angioplasty

6. Metabolic Obesity as a Predictor of Coronary Artery Disease

7. Antiplatelet Drugs Resistance Registry

8. A Retrospective Study of Treatment Pattern and Cost of Treatment in Methicillin-Resistant Staphylococcus aureus in Tertiary Care Hospital – Completed 

9. Assessment of protective effect of a Bioflavonoid, Quercetin in Dimethyl Benzanthracene- induced Breast cancer in Female Wistar Rats

10. Resveratrol Chemoprotective effect and COX 2 Down regulation in Tumor suppression in DMBA induced Breast cancer in Female Sprague Dawley rats

 

CONFERENCES & PAPER PRESENTATIONS: 

International (Outside India):

 

1. “Heart Failure 2019 & World Congress on Acute Heart Failure” from 25th May 2018 to 28th May 2019 at Athens, Greece. 

 

Paper presentations:

I. Healthcare Expenditure of Patients with Heart Failure in a Developing Country

II. Drug utilization patterns and its impact on health resource utilization and outcomes among patients with heart failure at a tertiary care hospital in southern India

 

Late Breaking Trial Presentation:

 

III. Impact of hypertension on heart failure outcomes: insights from Manipal Heart Failure Registry [MHFR], India

2. “Heart Failure 2018 & World Congress on Acute Heart Failure” from 26th May 2018 to 29th May 2018 at Vienna, Austria. 

 

Paper presentations:

I. Role of emergency medical system and early intervention by specialist cardiologist/heart failure expert in influencing the clinical outcomes in Manipal Heart Failure Registry [MHFR] patients

II. Quality of life and mortality on 1 year follow up in Manipal Heart Failure Registry [MHFR]

Late Breaking Trial Presentation:

III. Manipal Heart Failure Registry (MHFR): A Long Term, Prospective and

 

Descriptive Study of Heart Failure in a Tertiary Care Hospital in South India 

3. American College of Cardiology (ACC) Middle East Conference 2017, on October 19-21, 2017 at Dubai, UAE. 

“Paper Presentation; Topic: Descriptive analysis of Health related quality of life in heart failure patients [Preliminary data of Manipal Heart Failure Registry (MHFR) study]”

International (In India):

1. Alexander Von Humboldt Indo-German Research Colloquium on November 22-24, 2017 at The Leela Palace, Bangalore. 

[Paper Presentation; Assessment of one-year mortality and health related quality of life in heart failure patients of manipal heart failure registry [MHFR] study]

2. 1st International Conference on Healthcare and Technical Research (ICHTR 2015), December 22-24, 2015 at Manipal University, Manipal, IN 

[Oral Presentation; Topic: Analysis of Risk Factors of Death in H1n1 Influenza Patients in a Tertiary Care Hospital]

3. International Conference on Recent Advances in Research and Treatment of Human Diseases. January 9-11, 2015 at IICT Hyderabad, IN 

[Oral Presentation; Topic: Body Image and Sexual Problem in Young Breast Cancer Patients in South Indian Population]

4. Global Cancer Conference & Medicare Summit 2014- Recent Advances in Cancer Diagnosis and Therapy, September 15-17, 2014, Hyderabad, IN 

[Oral Presentation; Topic: Body Image and Sexual Problem in Young Breast Cancer Patients in South Indian Population] National:

1. Evidence Based Healthcare Society of India annual conference (EBMCON 2019), 2-4 January 2019

[Oral Presentation: Drug utilization patterns and its impact on health resource utilization and outcomes among patients with heart failure at a tertiary care hospital in southern India; Prize for best paper presentation]

2. Manipal Cardiology update on November 1, 2017 organized by Department of Cardiology, Kasturba Medical College, Manipal University. 

[Organizing Committee Member & Oral Presentation; Topic: Manipal Heart Failure Registry (MHFR): The First Indian Long Term Heart Failure Registry]

[Poster Presentation; Topic: Health related quality of life in heart failure patients [Six months data of Manipal Heart Failure Registry (MHFR) study]

[Poster Presentation; Healthcare Resources Utilization in Heart Failure Management [6 months data of Manipal Heart Failure Registry (MHFR) study]

3. 5th Annual Conference of the Society for Heart Failure and Transplantation to be held at Calicut on 23/24 September 2017.   [Case presented in best cases category: Spontaneous Improvement of QRS width and LV Reverse Remodeling by Optimal Medical Therapy- Best case presentation category award]

4. Impact of Global Issues on Women and Children held from 9th to 12th January 2017 by Manipal College of Nursing, Manipal University, Manipal   [Oral presentation; Topic: What makes me worried after breast cancer? The threatening outcomes]

5. Manipal Cardiology update on November 1, 2016 organized by Department of Cardiology, Kasturba Medical College, Manipal University.   [Oral Presentation & Organizing Committee Member; Topic: Procedural Hemoglobin Loss Following Percutaneous Transluminal Coronary Angioplasty (PTCA) in a South Indian Tertiary Care Hospital]

6. 4th Annual Conference of the Society for Heart Failure and Transplantation to be held at Kochi on 03/04 September 2016

7. South Asian LA-APPENDAGE occlusion summit –27th March 2016, organized by Department of Cardiology, KMC, Manipal. (Organizing Committee Member)

8. Manipal Cardiac Update on November 1, 2015 organized by Department of Cardiology, Kasturba Medical College, Manipal University. (Organizing Committee Member)

9. 65th Indian Pharmaceutical Congress held at Noida-Delhi on December 21-23, 2013. [Poster Presented; Topic: Herpes simplex keratitis-induced endophthalmitis in a patient with AIDS with disseminated tuberculosis].

10. 26th Kerala Science Congress, Wayanad, Kerala on January 27-31, 2014   [Poster Presented; Topic: Herpes simplex keratitis-induced endophthalmitis in a patient with AIDS with disseminated tuberculosis].

11. South Zone Interventional Council Conference-2014 (SIC-CON 2014), January 24-26, 2014, KMC Manipal, IN

12. National            symposium            on       “Pharmacoeconomics,    Outcomes    Research and  Pharmaceutical care guidelines for India” February 12, 2014 Organized by ISPOR India-Karnataka Chapter and Association of Community  Pharmacists of India (ACPI) at Manipal College of Pharmaceutical Sciences, Manipal, India

13. “Cognition- Cell to System” held on February 21-22, 2014 at Sirdi Sai Baba Cancer Hospital, Manipal University. (Worked as Volunteer)

14. Manipal Cardiac Update 2014 organized by Dept. of Cardiology, Kasturba Medical College, Manipal University.

15. Indo-Queensland joint venture 2013 “Food as Medicine” held at MCOPS, Manipal.

16. Manipal Cardiac Update 2013 organized by Dept. of Cardiology, Kasturba Medical College, Manipal University.

17. Manipal Cardiac Update 2012 organized by Dept. of Cardiology, Kasturba Medical College, Manipal University. 

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