Name: Dr. Ajit Singh
Journal Role: Associate editor
Designation: Ph.D. (cardiology)
Co-founder & Chief Executive Officer: CliMed Research Solutions,
University: Manipal Academy of Higher Education, Manipal University, India.
Country: India
Email: ceo@climed.in; Ajithsingh.mcops@gmail.com
Area of Interest: Clinical Research, Cardiology,
Pharmacoeconomics and Epidemiological studies.
BIOGRAPHY: He completed his Ph.D in Cardiology from Manipal University and
now he is a CEO Of his own company CliMed Research Solutions.
Education Qualifications
1. Ph.D.; Department of Cardiology, KMC, MAHE,
Manipal; 2019 Passed out.
2. Pharm.D; Manipal College Of Pharmaceutical Sciences
(MCOPS), Manipal; 2015 Passed out.
3. B.Pharm; Uttar Pradesh Technical University
(UPTU), Lucknow; 2012 Passed out.
4. B.Sc; CCS University, Meerut; 2009 Passed
out.
Work Experience:
1. CEO; CliMed Research Solutions
2. Guest faculty of Cardiac Pharmacology,
Manipal Academy of Higher Education, Manipal University, India. [2016-2019]
3. Principal Investigator of Manipal Heart
Failure Registry (MHFR) Study [since 2015]
4. Site Coordinator for phase III clinical
trial ‘PARALLAX-HF’ by Novartis Pharma Pvt. Ltd. [2017-2019]
5. Investigator of a global Heart Failure
clinical study ‘REPORT-HF’ by Novartis Pharma Pvt. Ltd. [2015-2018]
6. Research Associate at Manipal Center for
Clinical Research (MCCR) & Department of Cardiology, KMC, Manipal
University. [2015-2019]
Memberships:
1. European Society of Cardiology Professional
MID: 715803
2. American College of Cardiology MID: 3032286
3. International Society for Pharmacoeconomics
and Outcomes Research (ISPOR) MID: 28232.
Grants & Awards:
1. “Young Scientist Award 2020” by VD Good
Professional Association.
2. “Young Achievers Award 2019” for research
by Institute of Scholars, India
3. Department of Science and Technology (DST)-
SERB, International Travel Support to attend “Heart Failure 2019 & World
Congress on Acute Heart Failure” from 25th May 2019 to 28th May 2019 at Athens,
Greece
4. European Society of Cardiology, Travel
grant to attend “Heart Failure 2019 & World Congress on Acute Heart
Failure” from 25th May 2019 to 28th May 2019 at Athens, Greece
5. Indian Council of Medical Research (ICMR)
International Travel Support to attend
“Heart Failure 2018 & World Congress on Acute Heart Failure” from
26th May 2018 to 29th May 2018 at Vienna, Austria
6. European Society of Cardiology, Travel
grant to attend “Heart Failure 2018 & World Congress on Acute Heart
Failure” from 26th May 2018 to 29th May 2018 at Vienna, Austria
7. Alexander Von Humboldt Indo-German Research
Colloquium, Bangalore. (November 22-24, 2017)- Travel and accommodation
reimbursement by AVH Foundation, Germany
8. ACC Middle East Conference 2017, Dubai
(October 19-21, 2017); grant for registration and participation
9. TMA Pai scholarship for full time PhD at
Manipal Academy of Higher Education (From January 2016 to May 2019)
10. Consolation prize for “Optical Device to
Monitor blood Platelets Aggregation” at Manipal University Innovation Award
held on October 28, 2017
Other Journal Involvements:
ASSOCIATE EDITOR:
3 Journals including -Asian Journal of
Pharmaceutical Research
REVIEWER:
13 Journals including -
1. BMJ Case Reports
2. Clinical Toxicology (Oxford Journals)
3. Clinical Rheumatology (Springer)
4. ISPOR, Value In Health Regional Issues
(VIHRI)
PUBLICATIONS:
Google Scholar
https://scholar.google.com/citations?user=wFAkOe4AAAAJ&hI=en&oi=sra
ORCID
https://orcid.org/0000-0001-5767-6384
Researcher id
https://publons.com/researcher/2510909/ajit-singh/
Scopus id
https://www.scopus.com/authid/detail.uri?authorId=57191972713
PUBLICATION WORKS
1. Azilsartan causing metabolic
encephalopathy. Anujith G. Sekhar1, Ajit Singh, Sheetal Chauhan, Kanav Khera,
Tom Devasia. J Appl Pharm Sci, 2020; 10(06):123-125.
2. Financial burden of heart failure in a
developing country: cost analysis from Manipal Heart Failure Registry, India.
Singh A, Chauhan S, Devasia T, Rao Y, Paramasivam G, Shetty PN, Uppunda D,
Kareem H. India. J Public Health (Berl.) 2019. https://doi.org/10.1007/s10389-01901141-w
3. Outcomes of the patients of heart failure
with reduced ejection fraction receiving inotropic support in initial 6 hours:
Insights from Manipal Heart Failure Registry.
Singh A, Chauhan S, Paramasivam G, Devasia T, Rao Y, Shetty PN, Amin N,
Uppunda D, Kareem H. J Appl Pharm Sci, 2019; 9(08):011–017.
4. Insulin resistance and the severity of
coronary artery disease based on obesity status in stable-angina patients: A
cross-sectional analysis. Uppunda D,
Shetty R, Rao P, Razak A, Singh A, Chauhan S, Vadnagarwala H, Prabhu S, Pai U.
J Appl Pharm Sci, 2019; 9(07):091–094.
5. Association of Metabolic Obesity and BMI
Status with Severity of Angiographic Coronary Artery Disease in Stable Angina
Patients. Uppunda D, Shetty RK, Rao P, Razak A, Ravishanker, Shetty K, Chauhan
S, Singh A. Journal of Clinical and Diagnostic Research. 2019 Apr, Vol-13(4):
OC04-OC08.
6. Impact of socioeconomic status on adverse
cardiac events after coronary angioplasty: a cohort study. Kareem, H., Shetty, P., Devasia, T., Karkala,
Y., Paramasivam, G., Guddattu, V., Singh, A. and Chauhan, S. (2018). Heart
Asia, 10(2), p.e010960.
7. Manipal lifestyle modification score to
predict major adverse cardiac events in postcoronary angioplasty patients. Devasia, T., Shetty, P.N., Kareem, H.,
Karkala, Y.R. and Singh, A., 2018. Indian Heart Journal.
8. Baseline NT-ProBNP Level as a Risk
Predictor of Contrast Induced-Acute Kidney Injury in Acute Coronary Syndrome
Patients Undergoing Primary Angioplasty.
Agarwal, S., Kareem, H., Devasia, T., Mallu, R.R., Paramasivam, G.,
Singh, A., Shetty, P.N. and Dhanse, S., 2018. Journal of Clinical &
Diagnostic Research, 12(3).
9. Glycosylated Haemoglobin as a Risk
Predictor of Coronary Artery Disease in Patients with Stable Angina. Uppunda, D., Shetty, K., Shetty, P.N., Singh,
A., Shetty, R.K., Rao, P. And Razak, A., 2018. Journal of Clinical &
Diagnostic Research, 12(9).
10. Breast Cancer and the Heart: Burden on the
Chest. Singh, A., Kareem, H., Devasia,
T., Khera, K., Chauhan, S., K, Y. and P, G. (2018). Journal of Cardiovascular
Disease Research, 9(1), pp.01-04.
11. Cisplatin-Etoposide Induced Myocardial
Infarction in a Patient with Small Cell Carcinoma. Katta, S., Chauhan, S., Singh, A., Shetty,
P.N., Kareem, H. and Devasia, T., 2018. Journal of Applied Pharmaceutical
Science Vol, 8(05), pp.139-142.
12. Atorvastatin-Induced Hepatotoxicity,
Increased by Clopidogrel Stress on CYP450 Enzyme: Understanding the Mechanism
through a Case. Thotakura, S., Singh,
A., Khera, K., Chauhan, S. and Devasia, T., 2018. Journal of Applied
Pharmaceutical Science Vol, 8(04), pp.168-170.
13. Diabetes Mellitus and Metformin: Fatal
Vitamin B12 Deficiency Associated with Anemia and Sepsis in a Young Adult. Katroth, A., Narayanam, A., Chauhan, S. and
Singh, A., 2018. Journal of Applied Pharmaceutical Science Vol, 8(03),
pp.165-167.
14. Craniovertebral junction compression due
to posterior c1 arch in morquio syndrome: A diagnostic dilemma. Khan, B.H., Singh, A., Menon, G. and Devasia,
T., 2018. Journal of Clinical and Diagnostic Research, 12(4), pp.OJ01-OJ02.
15. Graded Exercise Therapy and Six Minute
Walk Test: The Modern Care of Peripheral Vascular Disease. Singh, A., Kareem, H., Devasia, T., Shetty,
P.N., Chauhan, S. and Rao, Y.K., 2017. Research Journal of Pharmacy and
Technology, 10(11), pp.4099-4101.
16. Association between the weight loss and
anxiety, depression after percutaneous transluminal coronary angioplasty: a
need for pre-discharged counseling.
Shetty, P.N., Devasia, T., Rao, Y., Singh, A. and Karim, H., 2017. Asian
Journal of Pharmaceutical and Clinical Research, 10(8), pp.323-326.
17. An infant with congenital rubella syndrome
in developing India. Singh, A., Narula,
S., Kareem, H. and Devasia, T. (2017). BMJ Case Reports, pp.bcr2017-221665.
18. Descriptive Analysis of Mortality
Predictors in H1n1 Influenza in South Indian Patients. Singh A, Khera K, Agarwal J, Awasthi S,
Francis J, Thunga G et al. Infectious Disorders - Drug Targets. 2017;17(2).
(PubMed ID: 28403799)
19. Registry Disease Studies in Cardiology in
India: The Need of the Hour. Karkal YR,
Tom D, Singh A, Shetty PN.Journal of Cardiovascular Disease Research, Vol 7,
Issue 4, Oct-Dec, 2016. 158-9.
20. “Multiple drugs causing severe anemia in
infective endocarditis” Singh A, Shetty
PN, Singh BM, Devasia T. Cardiovasc Hematol Disord Drug Targets. 2016 May 24.
(PubMed ID: 27215287)
21. Fatal prognosis of h1n1 influenza in late
trimester of pregnancy: descriptive analysis of four cases. Singh A, Khera K, Agarwal J, Awasthi S,
Francis JM, Thunga G.International Journal of Pharmacy and Pharmaceutical
Sciences. Vol 8, Issue 8, 2016 (SCOPUS indexed)
22. Cyclophosphamide-induced fatal cytopenia:
a case of paraquat poisoning. Singh A,
Rajesh V, Sekhar S, Shastri BA, Saravu K. Int J Pharm Pharm Sci
2016;8(10):296-297 (SCOPUS indexed)
23. “Seizure relapse based upon withdrawal
period of Anti-epileptic drugs in Pediatrics patients”. Rana R, Das S, Ramesh S, Chidambaramnathan S,
Swami A, Singh A. Archives of Pharmacy Practice. (DOI:
10.4103/2045-080X.137544)
24. Job's syndrome in a pediatric patient:
Case report and the clinical review.
Singh, A., Khera, K., Karanam, A. and Chauhan, S., 2015. Indian Journal
of Paediatric Dermatology, 16(2), p.96.
25. “Assessment of Adherence & Variation
in Color and Shape of Oral Antibiotic Pills”.
Rad LV, Rana R, Reddy S, Masoumi SA, Suresh A, Singh A. Asian Academic
Research Journal of Multidisciplinary, vol 1, issue 31; 2015.
26. “Neuro-Ophthalmic Complications In
Systemic Lupus Erythematosus: Case Analysis and the Literature Review” Singh A, Khera K, Karanam A, Chauhan S, Rana
R. International Journal of Biomedical Research, vol 6, issue 04; 2015.
27. Design and Evaluation of Transdermal Patch
of Felodipine. Chauhan, Singh A et al.
Indo American Journal of Pharmaceutical Research.2015:5(09).
28. Herpes simplex keratitis-induced
endophthalmitis in a patient with AIDS with disseminated tuberculosis. Singh, A., Khera, K., Inam, S. and Hande, H.
(2014). Case Reports, 2014(feb27 1), pp.bcr2013202804. bstracts in Indexed
Journals/PubMed:
29. Healthcare Expenditure of Patients with
Heart Failure in a Developing Country.
Singh A, Devasia T, Kareem H, Karkala YR, Chauhan S, Shetty PN, Rao S,
Ganesh P, Uppunda D. European Journal of Heart Failure (2019) 21 (Suppl. S1;pp.
277). [IF: 13.26]
30. Drug utilization patterns and its impact
on health resource utilization and outcomes among patients with heart failure
at a tertiary care hospital in southern India.
Singh A, Devasia T, Kareem H, Karkala YR, Chauhan S, Shetty PN Ganesh P.
European Journal of Heart Failure (2019) 21 (Suppl. S1;pp. 393). [IF: 13.26]
31. Role of emergency medical system and early
intervention by specialist cardiologist/heart failure expert in influencing the
clinical outcomes in Manipal Heart Failure Registry [MHFR] patients. Singh A, Devasia T, Kareem H, Karkala YR,
Chauhan S, Shetty PN, Rao S, Ganesh P, Uppunda D, Shetty KK. European Journal
of Heart Failure 2018 May 1 (Vol. 20, pp. 244). [IF: 10.86]
32. Quality of life and mortality on 1 year
follow up in Manipal Heart Failure Registry [MHFR]. Singh A, Devasia T, Kareem H, Karkala YR,
Chauhan S, Shetty PN, Rao S. European Journal of Heart Failure 2018 May 1 (Vol.
20, pp. 244). [IF: 10.86]
33. Assessment of statins resistance in the
patients underwent percutaneous transluminal coronary angioplasty and its
association with major adverse cardiac events.
Chauhan, S., Shetty, P., Devasia, T., Karkala, Y., Kareem, H. and Singh,
A. (2018). Indian Heart Journal, 70, pp.S30-S31.
34. Assessment of factors associated with
major adverse cardiac events after undergoing percutaneous transluminal
coronary angioplasty. Shetty, P.,
Devasia, T., Kareem, H., Rao K, Y., A., Singh, A., Uppunda, D. and Guddattu, V.
(2018). Indian Heart Journal, 70, p.S72.
35. One year outcomes and drug utilization
review in Manipal Heart Failure Registry (MHFR) patients. Singh, A., Devasia, T., Karkala, Y., Chauhan,
S., Kareem, H. and Shetty, P. (2018). Indian Heart Journal, 70, p.S52.
36. Metabolically obese status with normal BMI
is associated with the prevalence and severity of angiographic CAD in
stable-angina patients. Uppunda, D.,
Shetty, R., Rao, P. and Singh, A. (2018). Indian Heart Journal, 70, p.S8.
37. Impact of socio-economic status on adverse
cardiac events after undergoing percutaneous transluminal coronary angioplasty:
A cohort study. Shetty, P., Devasia, T.,
Kareem, H., Ganesh, P., Karkalla, Y., Guddattu, V. and Singh, A. (2017).Indian
Heart Journal, 69, p.S68.
38. Body Image and Sexual Problem in Young
Breast Cancer Patients in South Indian Population. Singh A, Rana R. Value in Health.
2015;18(7):A824. (IF: 3.28) (PubMed ID: 26534397)
39. Design And Evaluation of Transdermal Patch
of Felodipine. Singh A, Chauhan S. Value
in Health. 2015;18(7):A831. (IF: 3.28) (PubMed ID: 26534437)
40. Analysis of Risk Factors of Death in H1N1
Influenza Patients in a Tertiary Care Hospital.
Singh A, Khera K, Agarwal J et al. Value in Health. 2015; 18(3):A229.
(IF: 3.28)
41. Patient's Participation in Improvement of
Health Related Outcomes: The Better Care Plan.
Singh A, Khera K, Rana R, Chauhan S. Value in Health. 2014;17(7):A453.
(IF: 2.891)
42. “Body image and sexual problems in young
breast cancer patients in South Indian Population”. Singh A, Rana R, Kumar SD.
J Cancer Sci. Therapy (Special Edition). (DOI: 10.4172/1948-5956.S1.037). (IF:
4.203)
PROJECTS:
1. Manipal Heart Failure Registry (MHFR): A
Long Term, Prospective and Descriptive Study of Heart Failure in a Tertiary
Care Hospital in South India
2. Body Image and Sexual Problems in young
women with Breast Cancer
3. Better Care Plan- Participation of
Caregivers in treatment decision making
4. Manipal lifestyle modification score-
Completed
5. Impact of socioeconomic status on adverse
cardiac events after coronary angioplasty
6. Metabolic Obesity as a Predictor of
Coronary Artery Disease
7. Antiplatelet Drugs Resistance Registry
8. A Retrospective Study of Treatment Pattern
and Cost of Treatment in Methicillin-Resistant Staphylococcus aureus in
Tertiary Care Hospital – Completed
9. Assessment of protective effect of a
Bioflavonoid, Quercetin in Dimethyl Benzanthracene- induced Breast cancer in
Female Wistar Rats
10. Resveratrol Chemoprotective effect and COX
2 Down regulation in Tumor suppression in DMBA induced Breast cancer in Female
Sprague Dawley rats
CONFERENCES & PAPER PRESENTATIONS:
International (Outside India):
1. “Heart Failure 2019 & World Congress on
Acute Heart Failure” from 25th May 2018 to 28th May 2019 at Athens,
Greece.
Paper presentations:
I. Healthcare Expenditure of Patients with
Heart Failure in a Developing Country
II. Drug utilization patterns and its impact
on health resource utilization and outcomes among patients with heart failure
at a tertiary care hospital in southern India
Late Breaking Trial Presentation:
III. Impact of hypertension on heart failure
outcomes: insights from Manipal Heart Failure Registry [MHFR], India
2. “Heart Failure 2018 & World Congress on
Acute Heart Failure” from 26th May 2018 to 29th May 2018 at Vienna,
Austria.
Paper presentations:
I. Role of emergency medical system and early
intervention by specialist cardiologist/heart failure expert in influencing the
clinical outcomes in Manipal Heart Failure Registry [MHFR] patients
II. Quality of life and mortality on 1 year
follow up in Manipal Heart Failure Registry [MHFR]
Late Breaking Trial Presentation:
III. Manipal Heart Failure Registry (MHFR): A
Long Term, Prospective and
Descriptive Study of Heart Failure in a
Tertiary Care Hospital in South India
3. American College of Cardiology (ACC) Middle
East Conference 2017, on October 19-21, 2017 at Dubai, UAE.
“Paper Presentation; Topic: Descriptive
analysis of Health related quality of life in heart failure patients
[Preliminary data of Manipal Heart Failure Registry (MHFR) study]”
International (In India):
1. Alexander Von Humboldt Indo-German Research
Colloquium on November 22-24, 2017 at The Leela Palace, Bangalore.
[Paper Presentation; Assessment of one-year
mortality and health related quality of life in heart failure patients of
manipal heart failure registry [MHFR] study]
2. 1st International Conference on Healthcare
and Technical Research (ICHTR 2015), December 22-24, 2015 at Manipal
University, Manipal, IN
[Oral Presentation; Topic: Analysis of Risk
Factors of Death in H1n1 Influenza Patients in a Tertiary Care Hospital]
3. International Conference on Recent Advances
in Research and Treatment of Human Diseases. January 9-11, 2015 at IICT
Hyderabad, IN
[Oral Presentation; Topic: Body Image and
Sexual Problem in Young Breast Cancer Patients in South Indian Population]
4. Global Cancer Conference & Medicare
Summit 2014- Recent Advances in Cancer Diagnosis and Therapy, September 15-17,
2014, Hyderabad, IN
[Oral Presentation; Topic: Body Image and
Sexual Problem in Young Breast Cancer Patients in South Indian Population]
National:
1. Evidence Based Healthcare Society of India
annual conference (EBMCON 2019), 2-4 January 2019
[Oral Presentation: Drug utilization patterns
and its impact on health resource utilization and outcomes among patients with
heart failure at a tertiary care hospital in southern India; Prize for best
paper presentation]
2. Manipal Cardiology update on November 1,
2017 organized by Department of Cardiology, Kasturba Medical College, Manipal
University.
[Organizing Committee Member & Oral
Presentation; Topic: Manipal Heart Failure Registry (MHFR): The First Indian
Long Term Heart Failure Registry]
[Poster Presentation; Topic: Health related
quality of life in heart failure patients [Six months data of Manipal Heart
Failure Registry (MHFR) study]
[Poster Presentation; Healthcare Resources
Utilization in Heart Failure Management [6 months data of Manipal Heart Failure
Registry (MHFR) study]
3. 5th Annual Conference of the Society for
Heart Failure and Transplantation to be held at Calicut on 23/24 September
2017. [Case presented in best cases category:
Spontaneous Improvement of QRS width and LV Reverse Remodeling by Optimal
Medical Therapy- Best case presentation category award]
4. Impact of Global Issues on Women and
Children held from 9th to 12th January 2017 by Manipal College of Nursing, Manipal
University, Manipal [Oral presentation;
Topic: What makes me worried after breast cancer? The threatening outcomes]
5. Manipal Cardiology update on November 1,
2016 organized by Department of Cardiology, Kasturba Medical College, Manipal
University. [Oral Presentation &
Organizing Committee Member; Topic: Procedural Hemoglobin Loss Following
Percutaneous Transluminal Coronary Angioplasty (PTCA) in a South Indian
Tertiary Care Hospital]
6. 4th Annual Conference of the Society for
Heart Failure and Transplantation to be held at Kochi on 03/04 September 2016
7. South Asian LA-APPENDAGE occlusion summit
–27th March 2016, organized by Department of Cardiology, KMC, Manipal.
(Organizing Committee Member)
8. Manipal Cardiac Update on November 1, 2015
organized by Department of Cardiology, Kasturba Medical College, Manipal
University. (Organizing Committee Member)
9. 65th Indian Pharmaceutical Congress held at
Noida-Delhi on December 21-23, 2013. [Poster Presented; Topic: Herpes simplex
keratitis-induced endophthalmitis in a patient with AIDS with disseminated
tuberculosis].
10. 26th Kerala Science Congress, Wayanad,
Kerala on January 27-31, 2014 [Poster
Presented; Topic: Herpes simplex keratitis-induced endophthalmitis in a patient
with AIDS with disseminated tuberculosis].
11. South Zone Interventional Council
Conference-2014 (SIC-CON 2014), January 24-26, 2014, KMC Manipal, IN
12. National symposium
on “Pharmacoeconomics, Outcomes
Research and Pharmaceutical care guidelines for India” February
12, 2014 Organized by ISPOR India-Karnataka Chapter and Association of
Community Pharmacists of India (ACPI) at
Manipal College of Pharmaceutical Sciences, Manipal, India
13. “Cognition- Cell to System” held on
February 21-22, 2014 at Sirdi Sai Baba Cancer Hospital, Manipal University.
(Worked as Volunteer)
14. Manipal Cardiac Update 2014 organized by
Dept. of Cardiology, Kasturba Medical College, Manipal University.
15. Indo-Queensland joint venture 2013 “Food
as Medicine” held at MCOPS, Manipal.
16. Manipal Cardiac Update 2013 organized by
Dept. of Cardiology, Kasturba Medical College, Manipal University.