World Journal of Biotechnology

Editor Name: Teresa Rubio-Tomás

Designation: PhD

Country: Greece

University: University of Crete

Email: teresa.rubio.t111@gmail.com

Research Interest: epigenetics, cancer, liver, cirrhosis, ageing, neurodegenerative diseases, cellular plasticity, cellular senescence, metabolism

BIOGRAPHY

I completed a BSc in Biology and then a MSc in Biomedical Research, both of them in Pompeu Fabra University (UPF) in Barcelona, Spain. Then I moved to Greece to do a PhD in the study of the epigenetic regulation of liver cancer. My PhD was part of a Marie Skłodowska-Curie Initial Training Network, where I had the opportunity to travel to Sweden, Switzerland and Hungary to meet our collaborators and share our work with them. After that I have been working in IDIBAPS research centre in Barcelona, leading my own projects related to liver diseases, cell plasticity, aging and cellular senescence. In the meantime I completed a second MSc, in the field of Education.

PUBLICATIONS

Rueda-Robles A, Audano M, Álvarez-Mercado AI, Rubio-Tomás T*(*corresponding author). Functions of SMYD proteins in biological processes: What do we know? An updated review. Archives of Biochemistry and Biophysics. 2021 Nov 15;712:109040. doi: 10.1016/j.abb.2021.109040. Epub 2021 Sep 20. PMID: 34555372. Review

Rubio-Tomás T#, Rueda-Robles A#, Plaza-Díaz J, Álvarez-Mercado AI. Nutrition and cellular senescence in obesity-related disorders. The Journal of Nutritional Biochemistry. 2021 Sep 10:108861. doi: 10.1016/j.jnutbio.2021.108861. Epub ahead of print. PMID: 34517097. (#contributed equally) Review

Rubio-Tomás T. Novel insights into SMYD2 and SMYD3 inhibitors: from potential anti-tumoural therapy to a variety of new applications. Molecular Biology Reports. 2021 Sep 12. doi: 10.1007/s11033-021-06701-6. Epub ahead of print. PMID: 34510321.Review

Coll M, Ariño S, Martinez-Sánchez C, Garcia-Pras E, Gallego J, Moles A, Aguilar-Bravo B, Blaya D, Vallverdú J, Rubio-Tomás T, Lozano JJ, Pose E, Graupera I, Andrea Fernández-Vidal, Pol A, Bataller R, Geng JG, Ginès P, Fernandez M, Sancho-Bru P. Ductular Reaction Promotes Intrahepatic Angiogenesis Via Slit2-Robo1 Signaling. Hepatology. 2021 Sep 7. doi: 10.1002/hep.32140. Epub ahead of print. PMID: 34490644. Original article

Rueda-Robles A#, Rubio-Tomás T#, Plaza-Diaz J, Álvarez-Mercado AI.

Impact of Dietary Patterns on H. pylori Infection and the Modulation of Microbiota to Counteract Its Effect. A Narrative Review. Pathogens. 2021 Jul 10;10(7):875. doi: 10.3390/pathogens10070875. PMCID: PMC8308520. (#contributed equally) Review

Rubio-Tomás T. The SMYD family proteins in immunology: An update of their obvious and non-obvious relations with the immune system. Heliyon. 2021 Jun 24;7(6):e07387. doi: 10.1016/j.heliyon.2021.e07387. PMID: 34235289; PMCID: PMC8246384. Review

Blaya D#, Rubio-Tomás T#, Rodrigo-Torres D, Lozano J, Coll M, Argemi J, Altamirano J, Affò S, Morales-Ibanez O, Gratacós-Ginès J, Pose Pose E, Tanguy M, Issoufaly T, Rautou PE, Bataller R, Caballería J, Sancho-Bru P. Endothelial dysfunction markers predict short-term mortality in patients with severe alcoholic hepatitis. Hepatolology International. 2021 May 5. doi: 10.1007/s12072-021-10165-y. Epub ahead of print. PMID: 33954832. (#contributed equally) Original article

Vallverdú J, Martínez García de la Torre RA, Mannaerts I, Verhulst S, Smout A, Coll M, Ariño S, Rubio-Tomás T, Aguilar-Bravo B, Martínez-Sánchez C, Blaya D, Verfaillie CM, van Grunsven LA, Sancho-Bru P. Directed differentiation of human induced pluripotent stem cells to hepatic stellate cells. Nature Protocols. 2021 May;16(5):2542-2563. doi: 10.1038/s41596-021-00509-1. Epub 2021 Apr 16. PMID: 33864055. Original article

Aguilar-Bravo B, Rodrigo-Torres D, Ariño S, Coll M, Pose E, Blaya D, Graupera I, Perea L, Vallverdú J, Rubio-Tomás T, Dubuquoy L, Armengol C, Lo Nigro A, Stärkel P, Mathurin P, Bataller R, Caballería J, José Lozano J, Ginès P, Sancho-Bru P. Ductular Reaction Cells Display an Inflammatory Profile and Recruit Neutrophils in Alcoholic Hepatitis. Hepatology. 2019 May;69(5):2180-2195. doi: 10.1002/hep.30472. Epub 2019 Mar 12. PMID: 30565271. Original article

Rubio-Tomás T, Aguilar-Bravo B, Sancho-Bru P. Genetic Lineage Tracing of Biliary Epithelial Cells. Methods in Molecular Biology. 2019;1905:45- 57. doi: 10.1007/978-1-4939-8961-4_5. PMID: 30536089. Book chapter

CONFERENCE ATTEND

EMBO | EMBL Symposium: Metabolism Meets Epigenetics, virtual (17/11/2021-20/11/2021).

Selected speaker for 15-minutes short talk in the 2nd International Workshop on Translational Cancer Research that took place in the island of Mallorca, Spain (21/10/2021-22/10/2021).

Invited speaker to the University of Thessaly on May 26, 2021.

1st meeting of the Spanish Association of Hepatology that took place in San Sebastián, Spain (04/10/2019-05/10/2019).

International Cellular Senescence Association (ICSA) meeting that took place in Athens, Greece (09/09/2019-12/09/2019).

Spetses Summer School on Nuclear Receptors and Epigenomic Mechanisms in Human Disease and Ageing (FEBS Advanced Lecture Course) that took place in the island of Spetses, Greece (27/08/2017-01/09/2017).

Spetses Summer School on Nuclear Receptor Signaling in Physiology and Disease (FEBS Advanced Lecture Course) that took place in the island of Spetses, Greece (23/08/2015-28/08/2015).

Danube Epigenetics meeting that took place in Debrecen, Hungary (20/11/2014-22/11/2014).